Yes, the hub is identical
Same 5x114.3 PCD and same 60.1 mm centre bore: wheels from Lexus RZ bolt on and centre on Lexus RX350 without rings. You still need to check the offset and tyres, detailed below.
≈: width estimated from the original tyre size.
Wheel by wheel: offset and tyres
Each original wheel from Lexus RZ is compared with the one from Lexus RX350 of the same diameter: how much closer the wheel gets to the shock absorber or how far it sticks out of the wheel arch, and whether the tyre keeps the same overall diameter.
- ✓
≈7.5Jx18 ET35 · 235/60R18 — Fits like the original
Compared with the original ≈7.5Jx18 ET35 on Lexus RX350: shock absorber side 0 mm, wheel arch side 0 mm, tyre diameter +3.3 % : fit it with the original tyre size of Lexus RX350 (235/55R18), not that of Lexus RZ.
Comparison for guidance only (estimated width). Check in detail
Before fitting the wheels
An identical hub is not enough: offset, width and diameter change the position of the wheel, and larger calipers can touch a smaller wheel. Original wheels often use bolts or nuts with a specific seat: keep the fixings intended for the wheel, with the thread of Lexus RX350 (Ecrous - 12x1.50), tightened to the torque shown on its vehicle page. Finally, check that the size is among the approved fitments for your vehicle. This comparison is for guidance only: have the fitting approved by a professional.
And the other way round: wheels from Lexus RX350 on Lexus RZ?